Significance of antinuclear antibody in Indian patients with rheumatoid arthritis

This study aimed to understand the differences in disease duration, serological parameters, extra Articular Manifestation and treatment of Indian RA patients depending upon antinuclear antibody (ANA) positivity. was planned as a cross-sectional observational study, wherein 184 18 years above diagnosed tested for Antinuclear Antibody, who reported consultation at rheumatology department Medanta –The Medicity hospital from August 2020 February 2022 were enrolled this study. Patient’s demographic data, present complains, –articular features, seronegative associated medical conditions like CAD, HTN, DM, Tuberculosis, hypothyroidism etc, family history current previous collected on day with physician. Cross tables generated Chi square test used testing association comparison between groups. The included RA. ANA positivity rate 45.1% (n=83). majority female- 155(84.2%). There no significant observed groups terms gender, mean age, age onset, median duration.